OpenScholar

Search results

13 results found

A first-generation pediatric cancer dependency map.

Publication: Journal Article

Daria, Neekesh V., Guillaume Kugener, Lillian M. Guenther, Clare F. Malone, Adam D. Durbin, Andrew L. Hong, Thomas P. Howard, et al. 2021. “A First-Generation Pediatric Cancer Dependency Map.”. Nature Genetics 53 (4): 529-38.

Correction Synthetic Lethal Interaction between the ESCRTParalog Enzymes VPS4A and VPS4B in CancersHarboring Loss of Chromosome 18q or 16q

Publication: Report

Neggers, Jasper E., Brenton R. Paolella, Adhana Asfaw, Michael V. Rothberg, Thomas A. Skipper, Annan Yang, Radha L. Kalekar, et al. 2020. “Correction Synthetic Lethal Interaction Between the ESCRTParalog Enzymes VPS4A and VPS4B in CancersHarboring Loss of Chromosome 18q or 16q.”

Cancer research needs a better map.

Publication: Journal Article

Boehm, Jesse, M. J. Garnett, DJ Adams, HE Francies, TR Golub, WC Hahn, Iorio, JM McFarland, Parts, and Vazquez. 2021. “Cancer Research Needs a Better Map.”. Nature 589 (7843): 514-16.

Resources

Page

Depmap MetMap Drug Repurposing FireBrowse Cancer Cell Line Encyclopedia FireCloud Cancer Cell Line Factory Genome Data Analysis Center (GDAC) Project Achilles Gene Set Enrichment Analysis (GSEA) Connectivity Map Matrisome Project Clue Connectopedia Molecular Signatures Database (MSigDB) LINCS...

Selective modulation of a pan-essential protein as a therapeutic strategy in cancer

Publication: Journal Article

Malone, Clare F., Neekesh V. Dharia, Guillaume Kugener, Alexandra B. Forman, Michael V. Rothberg, Mai Abdusamad, Alfredo Gonzalez, et al. 2021. “Selective Modulation of a Pan-Essential Protein As a Therapeutic Strategy in Cancer”. Cancer Discov.

Duplex-Repair enables highly accurate sequencing, despite DNA damage

Publication: Journal Article

Xiong, Kan, Douglas Shea, Justin Rhoades, Timothy Blewett, Ruolin Liu, Jin H Bae, Erica Nguyen, Mike Makrigiorgos, Todd R Golub, and Viktor A Adalsteinsson. 2021. “Duplex-Repair Enables Highly Accurate Sequencing, Despite DNA Damage”. Nucleic Acids Res 50 (1).

Noncanonical open reading frames encode functional proteins essential for cancer cell survival

Publication: Journal Article

Prensner, JR, OM Enache, Luria, Krug, KR Clauser, JM Dempster, Karger, et al. 2021. “Noncanonical Open Reading Frames Encode Functional Proteins Essential for Cancer Cell Survival”. Nature Biotechnology.

Eric Lander to take an academic leave to serve as White House science advisor

News: January 15, 2021

Golub Lab

FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS

Publication: Journal Article

Ferraro, Gino B, Ahmed Ali, Alba Luengo, David P Kodack, Amy Deik, Keene L Abbott, Divya Bezwada, et al. 2021. “FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS”. Nat Cancer 2 (4): 414-28.