The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.
Zhou, Jiechao, Sarah D Wade, David Graykowski, Mei-Fang Xiao, Binhui Zhao, Lucia A A Giannini, Jesse E Hanson, et al. 2023. “The Neuronal Pentraxin Nptx2 Regulates Complement Activity and Restrains Microglia-Mediated Synapse Loss in Neurodegeneration.”. Science Translational Medicine 15 (689): eadf0141.