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Human MCF7 and A549 cells cytoplasm–nucleus translocation

Accession number BBBC014 · Version 1 Example images Positive Negative Biological application This 96-well plate has images of cytoplasm to nucleus translocation of the transcription factor NFκB in MCF7 (human breast adenocarcinoma cell line) and A549 (human alveolar basal epithelial) cells in...

P. vivax (malaria) infected human blood smears

Accession number BBBC041 · Version 1 Example images Description of the biological application Malaria is a disease caused by Plasmodium parasites that remains a major threat in global health, affecting 200 million people and causing 400,000 deaths a year. The main species of malaria that affect...

Human U2OS cells – compound-profiling Cell Painting experiment

Accession number BBBC022 · Version 1 Example Images Hoechst 33342 staining con A staining SYTO 14 staining WGA + phalloidin staining MitoTracker Deep Red staining Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular...

FiloData3D - Single A549 cells with filopodia (synthetic image data)

Accession number BBBC046 · Version 1 Example images The synthetic time-lapse image data of a CRMP-2-phospho-defective cell for the given fluorescence level facto(F) and anisotropy ratio (AR). The synthetic image data of a CRMP-2-phospho-defective cell for varying anisotropy ratios (ARs). The...

In The Media

National Academy of Medicine announces Anna as an Emerging Leader in Health and Medicine On September 14, 2021 the National Academy of Medicine (NAM) announced ten Emerging Leaders in Health and Medicine, including Anna Greka. These scholars have committed to a three-year term working...

Support the Center for Mendelian Genomics today

Support Rare Disease Research Today Rare diseases are not rare. While each individual condition may affect a small number of people, together they impact more than 300 million people worldwide. In the United States alone, an estimated 30 million Americans live with a rare disease. The Broad Center...

Policy

Jonathan leads community-driven standards development for technical and ethical standards as co-lead of the Global Alliance for Genomics and Health's (GA4GH) Data Use & Researcher Identity (DURI) Workstream. The GA4GH standards Jonathan leads or has had a significant role in shaping include: The...