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Education and Outreach
You can download teaching materials related to our group's research at the CellProfiler website here.
Funding
Since 2003, grants have been provided by...
Research
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Workflow
Workflow Turnaround The Broad CMG provides exome and/or whole genome sequencing at no cost to the collaborator for affected cases and relatives. This centralized service offers high quality sequencing and analysis, incorporating discovery of all classes of variation (including copy number variants...
Lab Policy and Culture
Photo credit: Juliana Sohn Our mission: To uncover biological knowledge and new medicines by developing advanced methods to quantify and mine the rich information present in images. Our motto: Measure everything, ask questions later. Our ethos: - We love to discover the inner workings of biological...
Human MCF7 cells – compound-profiling experiment
Accession number BBBC021 · Version 1 Example Images Actin disrupter Aurora kinase inhbitor Eg5 inhibitor Tubulin destabilizer Tubulin stabilizer Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each...
Human U2OS cells – Gene overexpression profiling experiment
Accession number BBBC037 · Version 1 Example images Description of the biological application The image set can be used to functionally annotate the genes through comparing their overexpression morphological profiles. Images Images from five fluorescent channels were captured at 20x magnification on...