Neuroscience: Strength in numbers.
Sheng, Morgan, Roberto Malinow, and Richard Huganir. 2013. “Neuroscience: Strength in Numbers.”. Nature 493 (7433): 482-3.
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Functional anatomy of neural circuits regulating fear and extinction.
Knapska, Ewelina, Matylda Macias, Marta Mikosz, Aleksandra Nowak, Dorota Owczarek, Marcin Wawrzyniak, Marcelina Pieprzyk, et al. 2012. “Functional Anatomy of Neural Circuits Regulating Fear and Extinction.”. Proceedings of the National Academy of Sciences of the United States of America 109 (42): 17093-8.
The postsynaptic organization of synapses.
Sheng, Morgan, and Eunjoon Kim. 2011. “The Postsynaptic Organization of Synapses.”. Cold Spring Harbor Perspectives in Biology 3 (12).
Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior.
Wöhr, Markus, Florence I Roullet, Albert Y Hung, Morgan Sheng, and Jacqueline N Crawley. 2011. “Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior.”. PloS One 6 (6): e20631.
Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.
Jo, Jihoon, Daniel J Whitcomb, Kimberly Moore Olsen, Talitha L Kerrigan, Shih-Ching Lo, Gilles Bru-Mercier, Bryony Dickinson, et al. 2011. “Aβ(1-42) Inhibition of LTP Is Mediated by a Signaling Pathway Involving Caspase-3, Akt1 and GSK-3β.”. Nature Neuroscience 14 (5): 545-7.
MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function.
Hussain, Natasha K, Honor Hsin, Richard L Huganir, and Morgan Sheng. 2010. “MINK and TNIK Differentially Act on Rap2-Mediated Signal Transduction to Regulate Neuronal Structure and AMPA Receptor Function.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 30 (44): 14786-94.
Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease.
Zeng, Hu, Jiahao Huang, Haowen Zhou, William J Meilandt, Borislav Dejanovic, Yiming Zhou, Christopher J Bohlen, et al. 2023. “Integrative in Situ Mapping of Single-Cell Transcriptional States and Tissue Histopathology in a Mouse Model of Alzheimer’s Disease.”. Nature Neuroscience 26 (3): 430-46.
Optogenetic polymerization and assembly of electrically functional polymers for modulation of single-neuron excitability.
Sessler, Chanan D, Yiming Zhou, Wenbo Wang, Nolan D Hartley, Zhanyan Fu, David Graykowski, Morgan Sheng, Xiao Wang, and Jia Liu. 2022. “Optogenetic Polymerization and Assembly of Electrically Functional Polymers for Modulation of Single-Neuron Excitability.”. Science Advances 8 (49): eade1136.
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Our Mission The audacious goal of the GRO is to build an atlas of the function of every base in the non-coding genome. We believe that achieving this goal will accelerate all aspects of genomic medicine by underpinning efforts to: understand the function of disease-associated variants, generate new...