NMDA receptors and BAX are essential for Aβ impairment of LTP.
Olsen, Kimberly Moore, and Morgan Sheng. 2012. “NMDA Receptors and BAX Are Essential for Aβ Impairment of LTP.”. Scientific Reports 2: 225.
Sameer Aryal, Ph.D.
he/him
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Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease.
Bingol, Baris, and Morgan Sheng. 2011. “Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease.”. Neuron 69 (1): 22-32.
Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.
Jo, Jihoon, Gi Hoon Son, Bryony L Winters, Myung Jong Kim, Daniel J Whitcomb, Bryony A Dickinson, Youn-Bok Lee, et al. 2010. “Muscarinic Receptors Induce LTD of NMDAR EPSCs via a Mechanism Involving Hippocalcin, AP2 and PSD-95.”. Nature Neuroscience 13 (10): 1216-24.
The Gene Regulation Observatory (GRO), Broad Institute
The Gene Regulation Observatory (GRO) is a collaborative community of scientists based at the Broad Institute, working together to build a functional, base resolved map of the non-coding genome and its regulatory functions.
Congrats Sarah, Fei, Jason and teams! Check out photoselective sequencing in Nature Methods
Congrats to Sarah Mangiameli, Haiqi Chen, Andrew Earl, Julie Dobkin, Daniel Lesman, Jason Buenrostro & Fei Chen on the publication of photoselective sequencing in Nature methods this month. https://www.nature.com/articles/s41592-023-01845-8
Min Jee Kwon, Ph.D.
she/her
Wei-Chao Huang, Ph.D.
he/him
JUMP Cell Painting protocol (v3) in press
The newly optimized version 3 of the protocol has been accepted! It is in press at Nature Protocols as Cimini et al. 2023.
Two publicly available portals to explore the data
Ardigen’s phenAID portal The phenAID JUMP-CP Explorer was created by the Ardigen Data Science and Software Development team to enable easy access and visualization of JUMP-CP data. The web-based application shows a phenotypic and structural representation of the data set colored by clusters. Users...