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FDX1 regulates cellular protein lipoylation through direct binding to LIAS

Publication: Journal Article

Dreishpoon, Margaret B, Nolan R Bick, Boryana Petrova, Douglas M Warui, Alison Cameron, Squire J Booker, Naama Kanarek, Todd R Golub, and Peter Tsvetkov. 2023. “FDX1 Regulates Cellular Protein Lipoylation through Direct Binding to LIAS”. J Biol Chem 299 (9).

JUMP Cell Painting protocol (v3) in press

News: December 01, 2022

The newly optimized version 3 of the protocol has been accepted! It is in press at Nature Protocols as Cimini et al. 2023.

Two publicly available portals to explore the data

News: March 28, 2023

Ardigen’s phenAID portal The phenAID JUMP-CP Explorer was created by the Ardigen Data Science and Software Development team to enable easy access and visualization of JUMP-CP data. The web-based application shows a phenotypic and structural representation of the data set colored by clusters. Users...

Data release & Manuscript in BioRxiv

News: March 28, 2023

We are excited to share that the JUMP Cell Painting Datasets now include most data components from all but one of the sources for the principal dataset (cpg0016), covering 116,000 chemical and over 20,000 genetic perturbations (covering ~15,000 genes). The first draft of metadata files are available...

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Blog: April 18, 2023

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Blog: April 18, 2023

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Thouis 'Ray' Jones, Sc.D.

Person:

Principal Investigator, Novo Nordisk Foundation Center, Broad Institute

Nataliia Kozhemiako, Ph.D.

Person:

Nataliia’s academic background is in neurobiology and biomedical physiology. During her Ph.D. studies at Simon Fraser University, Canada, she received extensive training in neuroimaging research using functional magnetic resonance imaging, magnetoencephalography, and electroencephalography (EEG)...

Which single cell technology is best?

News: December 13, 2022

Jason, Luca and others weigh on on which single cell technology is best (for which application...?) in a Nature Technology Feature: https://www.nature.com/articles/d41586-022-04426-5