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The Carpenter lab and Schreiber lab at the Broad Institute of MIT and Harvard developed Cell Painting, a microscopy assay that generates images that reflect cell response to treatments such as drug or genetic perturbations, in high-throughput (at a scale of 100,000+ perturbations). The Carpenter lab...

KIDNEY DISEASE Autosomal dominant MUC1 kidney disease (MKD, also known as ADTKD-MUC1, and formerly called MCKD1) is a rare hereditary renal disease that ultimately requires dialysis or kidney transplantation for patients. For decades, scientists had known the genetic “neighborhood” of the mutation...

Retinal Inherited retinal degenerations (IRDs) are characterized by progressive dysfunction and death of rod and cone photoreceptor cells, leading to vision loss, and are one of the most genetically diverse groups of inherited disorders. Identifying the genetic cause of patients’ IRD has become...

How to cite CellProfiler in publications (the project's survival depends on it!) CellProfiler for cells (feel free to cite the most recent) : Stirling DR, Swain-Bowden MJ, Lucas AM, Carpenter AE, Cimini BA, Goodman A (2021). CellProfiler 4: improvements in speed, utility and usability. BMC...

COBA’s mission is to catalyze the entire bioimage analysis software community. What have we accomplished thus far? Scientific Community Image Forum We created and sponsor the Scientific Community Image Forum. This forum has brought together dozens of open source image analysis platforms to one...

DeepProfiler DeepProfiler is a set of tools that allow you to use deep learning for analyzing imaging data in high-throughput biological experiments. Documentation and instructions for DeepProfiler can be found in our Handbook and the code is located on the GitHub page. Cytominer The Pycytominer...

CellProfiler is free, open-source software for quantitative analysis of biological images. No prior experience in programming or computer vision is required – this page is intended to help you get up and running. The quickest way to get up and running with CellProfiler is to: Download CellProfiler...