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Accession number BBBC031 · Version 1 Example images Description of the biological application We generated a synthetic HCS dataset simulating drugs perturbing the cell shape and the expressions of proteins (here represented by different colours). The dataset is useful for testing classification and...

We welcome contributions of the following: Image sets with descriptions and ground truth High-throughput image sets Published benchmarking results of algorithms applied to the BBBC image sets Corrections to existing descriptions or ground truth Feedback on the benchmarking methodology or other...

Accession number BBBC040 · Version 1 Example images Biological application An ideal small-molecule screening library would be enriched in non-redundant bioactive compounds that maximize the performance diversity of the library. The construction of such libraries would be aided by a rapid feedback...

Accession number BBBC050 · Version 2 Example images Biological application Cell dynamics during the early mouse embryogenesis change spatiotemporally. For understanding the mechanism of this developmental process, imaging cell dynamics by live-cell imaging of fluorescently labeled nuclei and...

Accession number BBBC021 · Version 1 Example Images Actin disrupter Aurora kinase inhbitor Eg5 inhibitor Tubulin destabilizer Tubulin stabilizer Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each...

Accession number BBBC037 · Version 1 Example images Description of the biological application The image set can be used to functionally annotate the genes through comparing their overexpression morphological profiles. Images Images from five fluorescent channels were captured at 20x magnification on...

Accession number BBBC003 · Version 1 Example images . DIC Image Foreground Biological application Fluorescence microscopy cannot be used to image human embryos to determine embryo viability for in vitro fertilization because the introduction of exogenous fluorescent dyes is considered a toxic...

Accession number BBBC010 · Version 1 Example images Positive: mostly alive Negative: mostly dead Biological application This selection of images are controls selected from a screen to find novel anti-infectives using the roundworm C.elegans . The animals were exposed to the pathogen Enterococcus...

Accession number BBBC018 · Version 1 Example Images ​ ​ ​ ​ ​ Actin blebs Actin dots Anaphase/Telephase Angular Cell Edges Cresent Nuclei ​ ​ ​ ​ ​ Long Projections Metaphase Motile Peas in a Pod Peripheral Actin ​ ​ ​ ​ Large Spread Phospho-histone H3 dots Prometaphase Prophase Biological...