Vijay Sankaran, M.D., Ph.D.
Jan Ellen Paradise, MD Professor of Pediatrics, Harvard Medical School Investigator, Howard Hughes Medical Institute Attending Physician, Dana-Farber/Boston Children's Cancer and Blood Disorders Center
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Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution.
Mangiameli, Sarah M, Haiqi Chen, Andrew S Earl, Julie A Dobkin, Daniel Lesman, Jason D Buenrostro, and Fei Chen. 2023. “Photoselective Sequencing: Microscopically Guided Genomic Measurements With Subcellular Resolution.”. Nature Methods 20 (5): 686-94.
A transcription factor atlas of directed differentiation.
Joung, Julia, Sai Ma, Tristan Tay, Kathryn R Geiger-Schuller, Paul C Kirchgatterer, Vanessa K Verdine, Baolin Guo, et al. 2023. “A Transcription Factor Atlas of Directed Differentiation.”. Cell 186 (1): 209-229.e26.
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models.
Rozowsky, Joel, Jiahao Gao, Beatrice Borsari, Yucheng T Yang, Timur Galeev, Gamze Gürsoy, Charles B Epstein, et al. 2023. “The EN-TEx Resource of Multi-Tissue Personal Epigenomes & Variant-Impact Models.”. Cell 186 (7): 1493-1511.e40.
Human genetic diversity alters off-target outcomes of therapeutic gene editing.
Cancellieri, Samuele, Jing Zeng, Linda Yingqi Lin, Manuel Tognon, My Anh Nguyen, Jiecong Lin, Nicola Bombieri, et al. 2023. “Human Genetic Diversity Alters Off-Target Outcomes of Therapeutic Gene Editing.”. Nature Genetics 55 (1): 34-43.
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.
Ma, Sai, Bing Zhang, Lindsay M LaFave, Andrew S Earl, Zachary Chiang, Yan Hu, Jiarui Ding, et al. 2020. “Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.”. Cell 183 (4): 1103-1116.e20.
Recruiting
Labs within the GRO are often hiring! Check out each GRO Investigator's profile to find a link to their lab page for more information. The team based at the Broad Institute is often hiring as well. You can search for open positions here.
GRO members Ardlie, Bernstein, Chen, and Buenrostro to contribute to the SMaHT common fund program
The Somatic Mosaicism across Human Tissues (SMaHT) Network aims to transform our understanding of how somatic mosaicism in human cells influences biology and disease. GRO members Kristin Ardlie, Jason Buenrostro, Fei Chen, and Bradley Bernstein (and their collaborators) were all awarded grants in...
Read a recent interview with GRO member Fei Chen
Meet the HSCRB Faculty: Fei Chen Fei Chen, PhD, is an assistant professor at the Harvard Department of Stem Cell and Regenerative Biology, and a Core Faculty member at the Broad Institute. Learn more about Fei and his research. Read more in a recent interview for the HSCRB faculty spotlight Explore...