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Research

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Understanding Ion Channel Biology in the Kidney and Beyond Investigating a New Pathway for Misfolded Protein Quality Control and Degradation Dissecting Lipotoxicity Pathways and their Effect on Proteostasis Harnessing Next-Generation Tools to Gain Insights at Single-Cell Resolution A major focus of...

CellProfiler 4.1 Release

Blog: April 27, 2021

Beth Cimini Hi all, We hope you’re enjoying our new CellProfiler 4.1 release! If you haven’t had a chance to see it yet, please do grab a copy from https://cellprofiler.org/releases. There are a few new features or changes of note we’re particularly excited to share with you all: For the first time...

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Published: "The ImageJ ecosystem: Open-source software for image visualization, processing, and analysis"

News: January 30, 2021

Protein Society journal Protein Science published a manuscript from co-PI Kevin Eliceiri's group highlighting the ImageJ codebase and community, including a review of the core features of the ImageJ ecosystem and how ImageJ has responded to imaging technology advancements with new plugins and tools...

Getting started using CellProfiler from the command line

Blog: April 30, 2021

Beth Cimini Cross posted from our GitHub wiki — check there for any future updates! Running CellProfiler from the command line has a major advantage — you don't need to spend computational power or memory creating the graphical user interface (GUI) that you're used to using in CellProfiler! It also...

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Anne Carpenter featured in "Automating Drug Discovery With Machine Learning"

News: April 16, 2021

Technology Networks recently published "Automating Drug Discovery With Machine Learning" by Neeta Ratanghayra and featured a section on image-based profiling for drug discovery. COBA's Anne Carpenter was featured and spoke about image-based profiling in general as well as the use of machine learning...

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Contribute to the BBBC

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We welcome contributions of the following: Image sets with descriptions and ground truth High-throughput image sets Published benchmarking results of algorithms applied to the BBBC image sets Corrections to existing descriptions or ground truth Feedback on the benchmarking methodology or other...

Resources

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Depmap MetMap Drug Repurposing FireBrowse Cancer Cell Line Encyclopedia FireCloud Cancer Cell Line Factory Genome Data Analysis Center (GDAC) Project Achilles Gene Set Enrichment Analysis (GSEA) Connectivity Map Matrisome Project Clue Connectopedia Molecular Signatures Database (MSigDB) LINCS...