Synapses and Alzheimer's disease.
Sheng, Morgan, Bernardo L Sabatini, and Thomas C Südhof. 2012. “Synapses and Alzheimer’s Disease.”. Cold Spring Harbor Perspectives in Biology 4 (5).
Kira Perzel Mandell, Ph.D.
she/her
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NMDA receptors and BAX are essential for Aβ impairment of LTP.
Olsen, Kimberly Moore, and Morgan Sheng. 2012. “NMDA Receptors and BAX Are Essential for Aβ Impairment of LTP.”. Scientific Reports 2: 225.
Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease.
Bingol, Baris, and Morgan Sheng. 2011. “Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease.”. Neuron 69 (1): 22-32.
Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.
Jo, Jihoon, Gi Hoon Son, Bryony L Winters, Myung Jong Kim, Daniel J Whitcomb, Bryony A Dickinson, Youn-Bok Lee, et al. 2010. “Muscarinic Receptors Induce LTD of NMDAR EPSCs via a Mechanism Involving Hippocalcin, AP2 and PSD-95.”. Nature Neuroscience 13 (10): 1216-24.
Min Jee Kwon, Ph.D.
she/her
Sameer Aryal, Ph.D.
he/him
Wei-Chao Huang, Ph.D.
he/him
The Gene Regulation Observatory (GRO), Broad Institute
The Gene Regulation Observatory (GRO) is a collaborative community of scientists based at the Broad Institute, working together to build a functional, base resolved map of the non-coding genome and its regulatory functions.
GRO members Ardlie, Bernstein, Chen, and Buenrostro to contribute to the SMaHT common fund program
The Somatic Mosaicism across Human Tissues (SMaHT) Network aims to transform our understanding of how somatic mosaicism in human cells influences biology and disease. GRO members Kristin Ardlie, Jason Buenrostro, Fei Chen, and Bradley Bernstein (and their collaborators) were all awarded grants in...