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Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases.
Koh, Byunghee, Shani T Gal Oz, Ryota Sato, Hung N Nguyen, Garrett Dunlap, Chrisopher Mahony, Chrissy Bolton, et al. 2025. “Functional and Dysfunctional T Regulatory Cell States in Human Tissues in RA and Other Autoimmune Arthritic Diseases.”. BioRxiv : The Preprint Server for Biology.
Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain receive the 2025 Merkin Prize at the Broad Institute for chimeric antigen receptor (CAR) T-cell therapy
This groundbreaking form of personalized cancer immunotherapy has had remarkable success — more than 45,000 cancer patients worldwide have been treated with CAR T-cell therapy, extending their lives and, in many cases, delivering complete and sustained remissions.
Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs.
Valencia, Cristian, Aparna Nathan, Joyce B Kang, Laurie Rumker, Hyunsun Lee, and Soumya Raychaudhuri. 2025. “Modeling Heterogeneity in Single-Cell Perturbation States Enhances Detection of Response EQTLs.”. Nature Genetics.
Bioimage Analysis Bootcamp
What Is the Bioimage Analysis Bootcamp? The Bioimage Analysis Bootcamp, established and organized by the Cimini Lab at the Broad Institute, is an intensive, week-long training designed to help biologists and researchers strengthen their image analysis skills. The course focuses on decision-making...
Support the Center for Mendelian Genomics today
Support Rare Disease Research Today Rare diseases are not rare. While each individual condition may affect a small number of people, together they impact more than 300 million people worldwide. In the United States alone, an estimated 30 million Americans live with a rare disease. The Broad Center...