Cancer Cell Line Encyclopedia (CCLE)

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16 results found

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

Publication: Journal Article

Garraway L, Widlund H, Rubin M, Getz G, Berger A, Ramaswamy S, Beroukhim R, Milner D, Granter S, Du J, et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature. 2005;436(7047):117–22.

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Publication: Journal Article

Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin A, Kim S, Wilson C, Lehár J, Kryukov G, Sonkin D, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 2012;483(7391):603–7.

Processed Data CCLE data Broad DepMap Portal : The most recently processed and up-to-date CCLE datasets along with many perturbation datasets. List of Cell lines Cell line annotations Genetic Data Merged mutation calls (Coding regions, germlin filtered) CCLE structural variants (SvABA calls) for 329...

Pharmacogenomic agreement between two cancer cell line data sets

Publication: Journal Article

Cancer Cell Line Encyclopedia Consortium, Genomics of Drug Sensitivity in Cancer Consortium. Pharmacogenomic agreement between two cancer cell line data sets. Nature. 2015;528(7580):84–7.

Quantitative Proteomics of the Cancer Cell Line Encyclopedia

Publication: Journal Article

Nusinow D, Szpyt J, Ghandi M, Rose C, McDonald R, Kalocsay M, Jané-Valbuena J, Gelfand E, Schweppe D, Jedrychowski M, et al. Quantitative Proteomics of the Cancer Cell Line Encyclopedia. Cell. 2020;180(2):387–402.e16.

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BRAF mutation predicts sensitivity to MEK inhibition

Publication: Journal Article

Solit D, Garraway L, Pratilas C, Sawai A, Getz G, Basso A, Ye Q, Lobo J, She Y, Osman I, et al. BRAF mutation predicts sensitivity to MEK inhibition. Nature. 2006;439(7074):358–62.

Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia

Publication: Journal Article

Jaffe J, Wang Y, Chan HM, Zhang J, Huether R, Kryukov G, Bhang H- eun, Taylor J, Hu M, Englund N, et al. Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. Nat Genet. 2013;45(11):1386–91.

Cancer Cell Line Encyclopedia (CCLE)

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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Pharmacogenomic agreement between two cancer cell line data sets

Quantitative Proteomics of the Cancer Cell Line Encyclopedia

Resources

News & Events

BRAF mutation predicts sensitivity to MEK inhibition

Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia