Predictions across the tree of life

Predictions across the tree of life

Here we provide computational predictions across the whole proteomes of 206 eukaryotes using the DeepLoc2.0-mito model. This collection contains the predicted mitoproteomes of 198 eukaryotes alongside the experimentally-defined mitoproteomes of 8 eukaryotes (six MitoTOL species and previously reported human and yeast). These tables provide a summary of the computational predictions and experimental evidence supporting mitochondrial localization. The proteins are ordered by species (based on NCBI taxonomy ID).

  • Chen M.Z., Stefely J.A., Bardon E.G., MitoCarta Tree of Life Consortium, Calvo S.E., Mootha V.K. Comparative analysis of mitochondrial proteomes across the tree of life. Cell 2026; 189 [doi: 10.1016/j.cell.2026.08.029]

Download the datasets:

MitoTOL_mitoproteomes5.55 MB
MitoTOL_whole_proteomes.zip32.09 MB