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Bhagyalakshmi Shankarappa

she/her

Person: Project Scientist in the Molecular Genetics Laboratory at the National Institute of Mental Health and Neurosciences (NIMHANS)

Dr Bhagyalakshmi Shankarappa is a Project Scientist in the Molecular Genetics Laboratory at the National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, where she leads and contributes to multidisciplinary research programs on the genetics and epigenetics of neuropsychiatric...

Integration of large, complex single-cell datasets with Harmony2.

Publication: Journal Article

Patikas, Nikolaos, Hongcheng Yao, Roopa Madhu, Soumya Raychaudhuri, Martin Hemberg, and Ilya Korsunsky. 2026. “Integration of Large, Complex Single-Cell Datasets With Harmony2.”. BioRxiv : The Preprint Server for Biology.

Kazumasa Shimofuruta

Person: Visiting Scientist, ONO Pharma

My interest is in identifying drug discovery targets by combining various omics technologies, including imaging, with AI. During this period, I will be in charge of analysis for the VISTA Consortium, exploring approaches to rare diseases using image analysis.

Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus

Publication: Journal Article

Mandell, Kira A. Perzel, Sean K. Simmons, Ajay Nadig, Zohreh Farsi, Wei-Chao Huang, Sameer Aryal, Min Jee Kwon, et al. 2025. “Meta-Analysis of the Brain Transcriptomes of Multiple Genetic Mouse Models of Schizophrenia Highlights Dysregulation in Striatum and Thalamus”. Translational Psychiatry.

An inflammatory and quiescent HSC subpopulation expands with age in humans.

Publication: Journal Article

Safina, Ksenia R, Basit Salik, Dylan Kotliar, Michelle Curtis, Jonathan D Good, Chen Weng, Shawn David, et al. 2026. “An Inflammatory and Quiescent HSC Subpopulation Expands With Age in Humans.”. Genome Biology.

Decoding cortical folding with deep learning: toward neurodevelopmental biomarkers of psychiatric disorders.

Publication: Journal Article

Auriau, Pierre, Antoine Grigis, Jean-François Mangin, Joël Chavas, Julien Laval, Vincent Frouin, Arnaud Cachia, et al. 2026. “Decoding Cortical Folding With Deep Learning: Toward Neurodevelopmental Biomarkers of Psychiatric Disorders.”. Journal of Neural Transmission (Vienna, Austria : 1996).

Building a container image with Podman

Blog: February 05, 2026

Authors: Esteban Miglietta and Nodar Gogoberidze In a previous post, we have already discussed what Docker containers are and how to build them. Here, we're going to talk about an alternative to Docker for managing containers: Podman. But first... What are software containers? Software containers...

COBA Phase I

Page

The Center for Open Bioimage Analysis (COBA) was supported by an NIH P41 grant through November 2025, advancing open, accessible bioimage analysis tools and training for the global research community. Through software development, education, and direct user support, COBA empowered scientists...

Akanksha Khorgade

Person: Senior Computational Associate

Akanksha joined Methods Development Lab in 2022 from the IDMP platform at Broad, where she worked at the junction of Malaria and vaccine efficacy studies. She joined Broad in 2019 after completing her M.Sc in Bioinformatics. Her background is in telecommunications engineering and software...

Differential functional consequences of GRIN2A mutations associated with schizophrenia and neurodevelopmental disorders

Publication: Journal Article

Shepard, Nate, David Baez-Nieto, Sumaiya Iqbal, Erkin Kurganov, Nikita Budnik, Arthur J. Campbell, Jen Q. Pan, Morgan H Sheng, and Zohreh Farsi. 2024. “Differential Functional Consequences Of GRIN2A mutations Associated With Schizophrenia and Neurodevelopmental Disorders”. Scientific Reports .