Stephen Fleming

Stephen directs the Cellarium AI Lab, part of the Methods Development Lab at the Broad Institute of MIT and Harvard. The team uses advanced machine learning techniques and probabilistic modeling to develop principled approaches to single-cell data analysis. Cellarium is developing a suite of tools to handle billion-cell-scale datasets, both on the data infrastructure side as well as on the model training side. The team has developed single-cell transcriptomic foundation models as well as scientific services including the Cell Annotation Service, and is especially excited to turn single-cell perturbation data into biological understanding.

Stephen joined the Broad Institute in 2018 after receiving his PhD in physics from Harvard University, where he worked on nanopore DNA sequencing experiments and instrumentation. He also holds an MPhil in physics from the University of Cambridge, where he was a Churchill Scholar in the Physics of Medicine program, in addition to BS degrees in physics and biochemistry, both from Case Western Reserve University.

Outside the lab, Stephen loves doing art projects, gardening, playing soccer and tennis, and reading, all with his 4-year old son.