Konrad Karczewski is a genome scientist, currently an Assistant in Investigation in the CGM at MGH and Associate Member at the Broad Institute. Konrad received his undergraduate degree in Molecular Biology from Princeton University and his PhD in Biomedical Informatics from Stanford University, where he studied how regulatory variation influences human biology and disease. In his postdoctoral research, he built tools for variant interpretation (LOFTEE) that are widely used across the field, as well as the world's largest public datasets of genetic variation (gnomAD) that provide critical insight into gene and variant function, as well as browser infrastructures to serve these results to the community. His lab's research is focused on assembling and analyzing massive public datasets of genetic variation, and developing novel strategies using these to aid in the interpretation of putative disease variants, in order to better distinguish causal disease variants and improve our understanding of human biology.
